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Several #links# self-sufficient reports have now demonstrated, nonetheless, that the reliance upon CpG designs regarding TLR9 account activation has limitations to man made phosphorothioate oligodeoxynucleotides (PS-ODNs), understanding that normal phosphodiester oligodeoxynucleotides (PD-ODNs) join along with trigger TLR9 using the 2�� deoxyribose backbone inside a sequence-independent fashion (L

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