Bcl-xL promoter incorporates two WT1 binding web pages 5'-GCGGGGGAGC-3' and 5'GAGCGGGAGT-3', that happen to be much like the consensus WTE motif 5'-GCGTGGGAGT-3' [12] at positions -307 to -298 and -301 to -292 upstream of your transcription commence internet site of BclxL gene (Fig 5A remaining). Bcl-2 promoter also is made up of 5 WT1 binding internet sites together with the consensus sequence 5'


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