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Arely the musosal lesion may possibly result by contiguity, as an example, skin lesion near the nasal or oral mucosa. This type will not evolve spontaneously to clinical cure, and if left untreated, develops to mutilation or destruction, affecting the good quality of life of individuals. Normally, remedy failures and relapses are typical within this clinical form [18,22,23]. In current years, the


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